It's human versus the apes in the final trailer for War for the Planet of the Apes. He may not have started the war and it may go against what he believes but it's survival of the fittest when Caeser goes up against the humans. Could the little girl be the key to peace between the humans and the apes? 

Caesar and his apes are forced into a deadly conflict with an army of humans led by a ruthless Colonel. After the apes suffer unimaginable losses, Caesar wrestles with his darker instincts and begins his own mythic quest to avenge his kind. As the journey finally brings them face to face, Caesar and the Colonel are pitted against each other in an epic battle that will determine the fate of both their species and the future of the planet.