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The Voyage of Doctor Dolittle finds a live-action Downey playing the unconventional doctor who can speak to CG animals. Rex Harrison played the title character in the original 1967 movie, while Eddie Murphy starred in a pair of hit comedies roughly 20 years ago. This version boasts an all-star cast including Tom Holland, Rami Malek, John Cena, Kumail Nanjiani, Selena Gomez, Emma Thompson, Ralph Fiennes, Octavia Spencer, Marion Cotillard, Michael Sheen, Antonio Banderas, Craig Robinson and Carmen Ejogo — most of whom voice Dolittle’s animal friends.

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